Like these diseases, multiple sclerosis is a condition of increased inflammation with autoimmunity. It is known that the blood-brain barrier is broken down in multiple sclerosis. It is now becoming clear, however, that like other autoimmune conditions, there is evidence to suggest that there is increased intestinal permeability in multiple sclerosis as well.[vc_column_text]In a new report, Swedish researchers, using an experimental rodent model for multiple sclerosis, have now confirmed that immune activation as a consequence of increased intestinal permeability may play a fundamental role in multiple sclerosis. Indeed, when multiple sclerosis was induced in these rodents, there was an almost immediate correlation with increased gut permeability, which, in retrospect, was certainly something that was anticipated and was then proven.
The integrity of the gut wall is clearly dependent upon healthy gut bacteria. That said, one important early life experience that tends to increase the diversity of the gut bacteria is being breastfed. We are now seeing literature to suggest that absence of breastfeeding is associated with an increased risk of multiple sclerosis in humans. Lack of breastfeeding is associated with alterations of the gut bacteria, and this may well explain why a lack of breastfeeding shows correlation with risk for asthma, obesity, ADHD and allergies.
So as it relates to MS, again, preventive medicine should focus on creating a healthy gut bacteria by favoring such things as vaginal delivery as opposed to cesarean delivery, minimizing antibiotic exposure and breastfeeding if at all possible.[vc_row_inner][vc_column_inner width="1/4"][vc_single_image image="73" img_size="medium" alignment="center"][/vc_column_inner][vc_column_inner width="3/4"][vc_empty_space height="5px"][vc_column_text]About Dr. Perlmutter: David Perlmutter, M.D., is an expert in the human microbiome, a board-certified neurologist, Fellow of the American College of Nutrition, America’s brain-health expert and #1 New York Times best-selling author.[/vc_column_inner][/vc_row_inner][vc_column_text]This information is intended for educational and informational purposes only. It should not be used in place of an individual consultation or examination or replace the advice of your health care professional and should not be relied upon to determine diagnosis or course of treatment.